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The incorporation of natural cycle IVF protocols has gained quite a lot of interest in recent years. In this procedure, we monitor the first half of the woman’s cycle without the use of any medication and we end with egg collection when conditions are right to activate oocyte maturation. Fertilisation then takes place in the lab together with embryo transfer so as to gather a specific number of eggs and increase the chances of success. Though natural cycle IVF may sound attractive since no medication is used, we should not forget that it does have certain disadvantages. It is a procedure that needs time to get results, a fact that makes it both time consuming and often exhausting for the couple. Also, when medication is not used there is always the risk of us not having any eggs in the end or that we don’t get natural ovulation in time, often creating in the meantime a lot of stress for the couple. Natural cycle IV is a useful tool but doesn’t suit everyone. A specialised reproductive gynaecologist can advise you if this will be appropriate for you and help you make the right decision.